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Report Title

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Pipeline Review, H1 2017

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Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Pipeline Review, H1 2017


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Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Pipeline Review, H1 2017



Executive Summary

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Pipeline Review, H1 2017

Summary

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Neuronal acetylcholine receptor subunit beta-2 is a protein encoded by the CHRNB2 gene. Acetylcholine binds to this receptor. This results in extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) pipeline Target constitutes close to 11 molecules. Out of which approximately 9 molecules are developed by companies and remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical and Discovery stages are 1, 1, 1, 5 and 1 respectively. Similarly, the universities portfolio in Preclinical and Discovery stages comprises 1 and 1 molecules, respectively. Report covers products from therapy areas Central Nervous System which include indications Smoking Addiction, Psychiatric Disorders, Alcohol Addiction, Attention Deficit Hyperactivity Disorder (ADHD), Cognitive Disorders, Cognitive Impairment, Dyskinesia, Major Depressive Disorder, Neurology and Pain.

The latest report Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Pipeline Review, H1 2017, outlays comprehensive information on the Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews key players involved in Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) targeted therapeutics development with respective active and dormant or discontinued projects.

The report is built using data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

The report provides a snapshot of the global therapeutic landscape for Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)

The report reviews Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources

The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages

The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities

The report reviews key players involved in Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) targeted therapeutics and enlists all their major and minor projects

The report assesses Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type

The report summarizes all the dormant and discontinued pipeline projects

The report reviews latest news and deals related to Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) targeted therapeutics

Reasons to buy

Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies

Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage

Identify and understand the targeted therapy areas and indications for Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)

Identify the use of drugs for target identification and drug repurposing

Identify potential new clients or partners in the target demographic

Develop strategic initiatives by understanding the focus areas of leading companies

Plan mergers and acquisitions effectively by identifying key players and it most promising pipeline therapeutics

Devise corrective measures for pipeline projects by understanding Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) development landscape

Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Table of Contents

List of Tables

List of Figures

Introduction

Global Markets Direct Report Coverage

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Overview

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Therapeutics Development

Products under Development by Stage of Development

Products under Development by Therapy Area

Products under Development by Indication

Products under Development by Companies

Products under Development by Universities/Institutes

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Therapeutics Assessment

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Companies Involved in Therapeutics Development

Catalyst Biosciences Inc

H. Lundbeck A/S

NeuroDerm Ltd

Saniona AB

Sopharma AD

Suven Life Sciences Ltd

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Drug Profiles

(nicotine + opipramol hydrochloride)-Drug Profile

Product Description

Mechanism Of Action

R&D Progress

cytisine-Drug Profile

Product Description

Mechanism Of Action

R&D Progress

NS-9283-Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecule to Agonize Alpha 4Beta 2 and Alpha 6Beta 2 Neuronal Nicotinic Receptor for Smoking Cessation-Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecule to Antagonize CHRNB2 and CHRNA4 for Psychiatric Disorders-Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecule to Antagonize nAChR Alpha-4 Beta-2 for Pain-Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecules to Antagonize CHRNB2 and CHRNA4 for Smoking Cessation-Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecules to Antagonize nAChR Alpha-4 Beta-2 for Neurological and Psychiatric disorders-Drug Profile

Product Description

Mechanism Of Action

R&D Progress

SUVN-911-Drug Profile

Product Description

Mechanism Of Action

R&D Progress

TC-8831-Drug Profile

Product Description

Mechanism Of Action

R&D Progress

TPI-202-Drug Profile

Product Description

Mechanism Of Action

R&D Progress

varenicline tartrate-Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Dormant Products

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Discontinued Products

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2)-Product Development Milestones

Featured News & Press Releases

May 25, 2017: Suven Life Sciences announces initiation of Phase 1 Clinical Trial and First Dosing of SUVN-911, a Neuronal Acetylcholine Nicotinic Receptor antagonist for Major Depressive Disorder

Mar 08, 2017: Achieve Life Sciences and OncoGenex Pharmaceuticals Announce Cytisine Symposium at the Annual Society for Research in Nicotine and Tobacco Conference (SRNT)

Dec 16, 2016: FDA Approves Removal Of Boxed Warning Regarding Serious Neuropsychiatric Events From CHANTIX (varenicline) Labeling

Sep 14, 2016: FDA Advisory Committees Recommend to Remove Boxed Warning in Labeling for Pfizer Smoking Cessation Therapy, CHANTIX (varenicline)

May 23, 2016: CHAMPIX (Varenicline) European Union Label Updated To Include New Safety And Efficacy Data From The EAGLES Clinical Trial Following Endorsement From CHMP

Apr 22, 2016: CHANTIX/CHAMPIX (Varenicline) Results From The Largest Global Clinical Trial Of Smoking Cessation Medicines Published In The Lancet

Sep 04, 2015: Quit-smoking drug safer than thought

Mar 09, 2015: FDA updates label for stop smoking drug Chantix

Mar 09, 2015: Suven Life secures One (1) Product Patent each in Eurasia and Israel

Oct 16, 2014: Statement Regarding FDA Advisory Committees Vote on CHANTIX

Oct 06, 2014: US District Court Dismisses All Claims Related To Pfizer Chantix

Jan 21, 2014: CHANTIX/CHAMPIX (varenicline) Demonstrates Smoking-Cessation Efficacy In Smokers Unwilling or Unable To Quit Abruptly

Jun 03, 2013: NIH Researchers Find Varenicline As Promising Treatment For Alcohol Dependence

Feb 28, 2013: Pfizer Pays $273m For Settlement Of Lawsuits Related To Anti-smoking Drug Chantix

Jan 24, 2013: Pfizer Chantix Demonstrates Efficacy In Smokers Who Previously Attempted To Quit Smoking With Chantix

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

To know more information on Purchase by Section, please send a mail to sales@kenresearch.com

List of Figures

Number of Products under Development by Stage of Development, H1 2017

Number of Products under Development by Top 10 Indications, H1 2017

Number of Products by Mechanism of Actions, H1 2017

Number of Products by Stage and Mechanism of Actions, H1 2017

Number of Products by Routes of Administration, H1 2017

Number of Products by Stage and Routes of Administration, H1 2017

Number of Products by Stage and Molecule Type, H1 2017

List of Tables

Number of Products under Development by Stage of Development, H1 2017

Number of Products under Development by Therapy Areas, H1 2017

Number of Products under Development by Indication, H1 2017

Number of Products under Development by Companies, H1 2017

Products under Development by Companies, H1 2017

Number of Products under Investigation by Universities/Institutes, H1 2017

Products under Investigation by Universities/Institutes, H1 2017

Number of Products by Stage and Mechanism of Actions, H1 2017

Number of Products by Stage and Route of Administration, H1 2017

Number of Products by Stage and Molecule Type, H1 2017

Pipeline by Catalyst Biosciences Inc, H1 2017

Pipeline by H. Lundbeck A/S, H1 2017

Pipeline by NeuroDerm Ltd, H1 2017

Pipeline by Saniona AB, H1 2017

Pipeline by Sopharma AD, H1 2017

Pipeline by Suven Life Sciences Ltd, H1 2017

Dormant Products, H1 2017

Dormant Products, H1 2017 (Contd..1), H1 2017

Discontinued Products, H1 2017

Single User License:
Report can be used by individual purchaser only

Site License:
Report can be shared by unlimited users within one corporate location, e.g. a regional office

Corporate User License:
Report can be shared globally by unlimited users within the purchasing corporation e.g. all employees of a single company

Catalyst Biosciences Inc

H. Lundbeck A/S

NeuroDerm Ltd

Saniona AB

Sopharma AD

Suven Life Sciences Ltd

Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) Therapeutic Products under Development, Key Players in Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) Therapeutics, Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) Pipeline Overview, Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) Pipeline, Neuronal Acetylcholine Receptor Subunit Beta 2 (CHRNB2) Pipeline Assessment


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